BDBM50535912 CHEMBL16857

SMILES [H][C@](C)(Cc1ccccc1)N(C)CC#C

InChI Key InChIKey=MEZLKOACVSPNER-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50535912   

TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50535912(CHEMBL16857)
Affinity DataIC50: 17nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50535912(CHEMBL16857)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of human microsomal MAO-A expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50535912(CHEMBL16857)
Affinity DataIC50: 17nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50535912(CHEMBL16857)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50535912(CHEMBL16857)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed