BDBM50535896 CHEMBL4562665

SMILES CCC(c1cc(OC)c(OC)cc1CCNC(=O)N1CCc2cc(OC)c(OC)cc2C1CC)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=MVSZCEGVSRAQNK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535896   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
National Research Council

Curated by ChEMBL
LigandPNGBDBM50535896(CHEMBL4562665)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium accumulation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
National Research Council

Curated by ChEMBL
LigandPNGBDBM50535896(CHEMBL4562665)
Affinity DataEC50:  2.61E+4nMAssay Description:Agonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular calcium accumulation by Fluo-4-AM probe-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed