BDBM50535381 CHEMBL4591419

SMILES CC(C)c1onc(c1COc1ccc(COc2ccc(cc2)C(O)=O)cc1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=VZLWLZNMMRMHRT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535381   

TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535381(CHEMBL4591419)
Affinity DataEC50:  300nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535381(CHEMBL4591419)
Affinity DataEC50:  360nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed