BDBM50535211 CHEMBL4561467

SMILES O=C(CCCCc1nnc[nH]1)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1

InChI Key InChIKey=RETKKMHFGPNHKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535211   

TargetAutotaxin(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535211(CHEMBL4561467)
Affinity DataIC50: 92nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535211(CHEMBL4561467)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed