BDBM50535069 CHEMBL4448648

SMILES Cn1c(C(OC(C)(C)C)C([O-])=O)c(-c2ccc3OCCCc3c2)c2ccccc12

InChI Key InChIKey=JEETZBQOULTRJG-UHFFFAOYSA-M

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50535069   

TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase A128T mutant expressed in Escherichia coli BL21(DE3) cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as reduction in LED...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase A128T mutant multimerization with N-terminal FLAG-tagged integrase A128T m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataEC50:  1.61E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase multimerization with N-terminal FLAG-tagged integrase expressed in Escheri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged LEDGF/p75 binding to recombinant full length N-terminal His-tagged HIV1 integrase expressed in Escherichia coli ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed