BDBM50534993 CHEMBL4469651

SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCN(CC(=O)[C@H]2CCCN2)CC1)N1CCOCC1

InChI Key InChIKey=JUJOPPKPEVAXKP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50534993   

LigandPNGBDBM50534993(CHEMBL4469651)
Affinity DataIC50: 6.08E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50534993(CHEMBL4469651)
Affinity DataIC50: 60nMAssay Description:Inhibition of PI3Kbeta (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50534993(CHEMBL4469651)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50534993(CHEMBL4469651)
Affinity DataIC50: 52nMAssay Description:Inhibition of PI3Kdelta (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50534993(CHEMBL4469651)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta N836D mutant (unknown origin) expressed in Sf21 cells co-expressing p85 by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed