BDBM50534989 CHEMBL4553432::US11905244, Compound 15

SMILES Cc1cc2cc(OCC(O)=O)ccc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=DEKMAOVLCRHVIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534989   

TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50534989(CHEMBL4553432 | US11905244, Compound 15)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of N-terminal His-tagged STEP catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
Texas A&M University System

US Patent
LigandPNGBDBM50534989(CHEMBL4553432 | US11905244, Compound 15)
Affinity DataIC50: 174nMAssay Description:Using the GFP-NFAT translocation assay method, the inhibitory activity of the selected compounds at 200 μM concentration was evaluated. As demon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent