BDBM50534744 CHEMBL4518586

SMILES Fc1ccc(CCN2CCN(CCc3ccc(F)cc3)CC2)cc1

InChI Key InChIKey=XBSMQRUOUHVHEY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534744   

TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50534744(CHEMBL4518586)
Affinity DataKi:  58nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50534744(CHEMBL4518586)
Affinity DataKi:  3.71E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed