BDBM50534741 CHEMBL122425

SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1

InChI Key InChIKey=GGMGOJAMKUNERH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50534741   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50534741(CHEMBL122425)
Affinity DataKi:  238nMAssay Description:Inhibition of [3H]dofetilide binding to human ERG expressed in HEK293 cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50534741(CHEMBL122425)
Affinity DataKi:  1.57E+3nMAssay Description:Inhibition of DAT in rat striatal synaptosomes assessed as reduction in [3H]DA uptake preincubated for 5 mins followed by [3H]DA addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50534741(CHEMBL122425)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed