BDBM50534630 CHEMBL4545438

SMILES COP(=O)(Nc1nn(cc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C

InChI Key InChIKey=DXFOEMZXVYYLGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50534630   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50: 75nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50: 335nMAssay Description:Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50: 335nMAssay Description:Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed