BDBM50534523 CHEMBL4560583

SMILES Oc1c(C#N)c(=O)[nH]c2cnccc12

InChI Key InChIKey=NPAMRWDIMURYSE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50534523   

TargetLysine-specific demethylase 2B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM2B using biotinylated H2N-RKSAPATGGV(KMe2)KPHRYRPGTV-NTPEGBiot as substrate after 2 hrs using 0.3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length human KDM5C using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM4C using biotinylated H2N-ARTKQTAR(KMe3)STGGKAPRKQLA-NTPEGBiot as substrate after 30 mins using 3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length human KDM5B using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 2 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed