BDBM50534368 CHEMBL4440365

SMILES CCN1C(=O)C2CCCCCN2c2nc(Nc3ccc(c(OC)c3)-n3cnc(C)c3)ncc12

InChI Key InChIKey=JRIOARNEVPTSKL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534368   

TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534368(CHEMBL4440365)
Affinity DataEC50:  46nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as reduction in amyloid beta 42 production after 22 hrs by electroch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed