BDBM50534357 CHEMBL4536273

SMILES C[C@@H](C(O)=O)c1ccc(c(F)c1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PGOBYHDWDSAXMB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534357   

TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534357(CHEMBL4536273)
Affinity DataEC50:  4.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP K595N/M596L Swedish mutant assessed as inhibition of amyloid beta 42 production measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed