BDBM50534353 CHEMBL4578751

SMILES COc1cc(Nc2nc3[C@@H](CCCCn3n2)c2ccc(F)cc2)ccc1-n1cnc(C)c1

InChI Key InChIKey=JBZSMPGPVMBGPN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534353   

TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534353(CHEMBL4578751)
Affinity DataEC50:  6nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed