BDBM50534306 CHEMBL4450897

SMILES COC1CCN(CC1)c1ccc(cc1)C1(CC(O)=C(Sc2ccccc2Cl)C(=O)N1)c1ccsc1

InChI Key InChIKey=XYENCVBPSGNPKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50534306   

TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534306(CHEMBL4450897)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534306(CHEMBL4450897)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of LDHA in human MiPaca2 cells assessed as inhibition of lactate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534306(CHEMBL4450897)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed