BDBM50534108 CHEMBL4452232

SMILES Cc1ccc(NC(=O)CN2C(=O)S\C(=C/c3ccc(o3)-c3cc(ccc3Cl)C(O)=O)C2=O)cc1

InChI Key InChIKey=DIKLBWZYGAQLJD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50534108   

TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50534108(CHEMBL4452232)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50534108(CHEMBL4452232)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50534108(CHEMBL4452232)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50534108(CHEMBL4452232)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed