BDBM50533761 CHEMBL4585811

SMILES Cc1onc(c1[C@@H]1C[C@](C)(N=C(N)S1)c1ccc(F)cc1F)-c1ccccc1

InChI Key InChIKey=BWFBSDSDXRHTPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533761   

TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50533761(CHEMBL4585811)
Affinity DataIC50: 160nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed