BDBM50533758 CHEMBL4527268

SMILES Cc1noc(C)c1[C@@H]1C[C@](C)(N=C(N)S1)c1sccc1Cl

InChI Key InChIKey=PDCWPTMYTUVZQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533758   

TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50533758(CHEMBL4527268)
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed