BDBM50533672 CHEMBL4448466

SMILES Cc1cc(NC(=O)Nc2cc(on2)C(C)(C)C)ccc1Oc1ncnc2[nH]ncc12

InChI Key InChIKey=AYAHXOMVALZRBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533672   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50533672(CHEMBL4448466)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed