BDBM50533558 CHEMBL4474441

SMILES COc1cc(ccc1-c1cnc(OCC(C)C)c(Cl)c1)C(=O)NS(C)(=O)=O

InChI Key InChIKey=IAWNWMDZDAMTKU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533558   

TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50533558(CHEMBL4474441)Copy SMILESCopy InChI

Affinity DataIC50: 350nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium channel protein type 5 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50533558(CHEMBL4474441)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells incubated for 3 to 5 mins at -50 mV holding potential by electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL