BDBM50533512 CHEMBL4458399

SMILES Cc1cn(cn1)-c1ccc(cc1F)-c1csc(Nc2c3CCCc3nn2C)n1

InChI Key InChIKey=XWWVQEYJLIHQAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533512   

TargetPresenilin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50533512(CHEMBL4458399)
Affinity DataIC50: 1.00E+3nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing wild-type human APP751 assessed as inhibition of Abeta42 level after 24 hrs by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed