BDBM50533477 CHEMBL4439895

SMILES CCc1ccc(\C=N\NC(=O)C2=C(Cl)c3ccc(Cl)cc3C2)s1

InChI Key InChIKey=AOQXJGFKAZTXFC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533477   

TargetSerine/threonine-protein kinase PLK1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50533477(CHEMBL4439895)
Affinity DataKd:  8.39E+4nMAssay Description:Binding affinity to GST-tagged PLK1 PBD (327 to 603 residues) (unknown origin) by NT-647 dye-based microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50533477(CHEMBL4439895)
Affinity DataKd:  2.51E+5nMAssay Description:Binding affinity to GST-tagged PLK1 PBD K540A mutant (unknown origin) by NT-647 dye-based microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed