BDBM50533237 CHEMBL4526347

SMILES Fc1ccc(cc1F)-c1cc(Nc2ccncc2)c2cc[nH]c2n1

InChI Key InChIKey=YBZAHHNJSRROLU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50533237   

TargetCytochrome P450 1A2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 631nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 631nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533237(CHEMBL4526347)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed