BDBM50533139 CHEMBL4556979

SMILES O=C(Cc1ccc(cc1)-c1ccncc1)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=YLXBWBPZHOOGOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533139   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50533139(CHEMBL4556979)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50533139(CHEMBL4556979)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed