BDBM50533132 CHEMBL4579057

SMILES Cc1cc(ccc1C(=O)NC1CC1)-c1cnn2c(NC[C@@H]3CC[C@H](O)CC3)cc(Oc3cccnc3)nc12

InChI Key InChIKey=SBJNHLMBJGPMMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533132   

TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533132(CHEMBL4579057)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533132(CHEMBL4579057)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed