BDBM50533131 CHEMBL4453553

SMILES Cc1cc(ccc1C(=O)NC1CC1)-c1cnn2c(NCC3CCOCC3)cc(Oc3ccccc3)nc12

InChI Key InChIKey=IQLHWBCBQVMSIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533131   

TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533131(CHEMBL4453553)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533131(CHEMBL4453553)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed