BDBM50533096 CHEMBL4456659

SMILES CNC(=O)Nc1cc(Oc2cncc(OC)c2)c(cn1)[C@H]1COCC[C@@H]1F

InChI Key InChIKey=UEILGMSMKNVYMP-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533096   

TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533096(CHEMBL4456659)
Affinity DataEC50:  170nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533096(CHEMBL4456659)
Affinity DataEC50:  170nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533096(CHEMBL4456659)
Affinity DataEC50:  180nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533096(CHEMBL4456659)
Affinity DataEC50:  180nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed