BDBM50533094 CHEMBL4574160

SMILES CNC(=O)Nc1cc(Oc2cncc(C)c2)c(cn1)C(C)CO

InChI Key InChIKey=ONLVFFJIOJFXPY-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533094   

TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533094(CHEMBL4574160)
Affinity DataEC50:  670nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533094(CHEMBL4574160)
Affinity DataEC50:  820nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533094(CHEMBL4574160)
Affinity DataEC50:  820nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533094(CHEMBL4574160)
Affinity DataEC50:  670nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed