BDBM50532608 CHEMBL4525688

SMILES Cn1c2ccc(Oc3cccc(OC(F)(F)F)c3)c(Cc3ccccc3)c2c(=O)n(CCCO)c1=O

InChI Key InChIKey=PWTMGKUYTSUJSG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532608   

TargetShort transient receptor potential channel 5(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50532608(CHEMBL4525688)
Affinity DataIC50: 1nMAssay Description:Inhibition of TRPC5 (unknown origin) transfected in HEK293/TREx cells assessed as blocking of inward/outward currents after 20 to 48 hrs in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50532608(CHEMBL4525688)
Affinity DataIC50: 1nMAssay Description:Inhibition of TRPC5 (unknown origin) transfected in HEK293/TREx cells assessed as blocking of inward/outward currents after 20 to 48 hrs in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50532608(CHEMBL4525688)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRPC5 (unknown origin) transfected in HEK293/TREx cells assessed as reduction of rise in intracellular Ca2+ concentration after 60 to 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50532608(CHEMBL4525688)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRPC5 (unknown origin) transfected in HEK293/TREx cells assessed as reduction of rise in intracellular Ca2+ concentration after 60 to 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed