BDBM50532557 CHEMBL4435789

SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)[C@@H](c1ccc2OCOc2c1)n1nc(C)ccc1=O

InChI Key InChIKey=LUQZWCBOERIKEO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532557   

TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532557(CHEMBL4435789)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]-ET-1 from human ETB receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532557(CHEMBL4435789)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]-ET-1 from human ETB receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532557(CHEMBL4435789)
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]-ET-1 from human ETA receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532557(CHEMBL4435789)
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]-ET-1 from human ETA receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed