BDBM50532432 CHEMBL4532693

SMILES Clc1cccc(c1)C(=O)Nc1ccc2c(c1)C(=O)NS2(=O)=O

InChI Key InChIKey=WJSNUMIOITZHKE-UHFFFAOYSA-N

Data  10 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50532432   

TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of carbonic anhydrase 9 in human HT-29 cells assessed as reduction in cell viability in presence of CoCl2-induced hypoxic conditions after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of carbonic anhydrase 9 in human HT-29 cells assessed as reduction in cell viability in presence of CoCl2-induced hypoxic conditions after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  39nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  39nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  68nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  68nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  95nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  95nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  589nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  589nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  763nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50532432(CHEMBL4532693)
Affinity DataKi:  763nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed