BDBM50532380 CHEMBL4522605

SMILES CNC(=O)COc1ccc(cc1)-c1c(C#N)c(NC(=O)c2cccc(C[C@H](N)C(O)=O)c2)n2c3ccccc3nc2c1C#N

InChI Key InChIKey=MLNOOVGSMCJSCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532380   

TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50532380(CHEMBL4522605)
Affinity DataIC50: 1.82E+4nMAssay Description:Competitive inhibition of [14C]-L-leucine uptake at LAT1 in human MCF7 cells preincubated for 5 mins followed by addition of substrate measured durin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50532380(CHEMBL4522605)
Affinity DataIC50: 1.82E+4nMAssay Description:Competitive inhibition of [14C]-L-leucine uptake at LAT1 in human MCF7 cells preincubated for 5 mins followed by addition of substrate measured durin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed