BDBM50532341 CHEMBL4516235

SMILES CC(C)N(CCc1ccc(F)cc1)Cc1ccc(CCCCCNC(=O)\C=C\c2cccnc2)cc1

InChI Key InChIKey=MODZVRCHYLDRBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532341   

TargetNicotinamide phosphoribosyltransferase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50532341(CHEMBL4516235)
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant NAMPT (unknown origin) using nicotinamide as substrate measured every 5 mins for 30 mins in presence of recombinant NMNAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50532341(CHEMBL4516235)
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant NAMPT (unknown origin) using nicotinamide as substrate measured every 5 mins for 30 mins in presence of recombinant NMNAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed