BDBM50532282 CHEMBL4539512

SMILES COc1cc(cc2nc(-c3cc4ccccc4n3CC3CC3)n(C)c12)C(=O)N1CC[C@@H](O)[C@@H](N)C1

InChI Key InChIKey=BDYDINKSILYBOL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50532282   

TargetProtein-arginine deiminase type-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532282(CHEMBL4539512)
Affinity DataIC50: 50nMAssay Description:Displacement of GSK215 from full length PAD4 (unknown origin) after 50 mins by fluorescence polarization assay in absence of calciumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532282(CHEMBL4539512)
Affinity DataIC50: 50nMAssay Description:Displacement of GSK215 from full length PAD4 (unknown origin) after 50 mins by fluorescence polarization assay in absence of calciumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532282(CHEMBL4539512)
Affinity DataIC50: 50nMAssay Description:Inhibition of PAD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532282(CHEMBL4539512)
Affinity DataIC50: 250nMAssay Description:Inhibition of PAD4 (unknown origin) in presence of 2 mM CaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50532282(CHEMBL4539512)
Affinity DataIC50: 50nMAssay Description:Inhibition of PDE4 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed