BDBM50532257 CHEMBL1671905

SMILES CN1CC(=O)N2C(Cc3c([nH]c4ccccc34)C2c2ccc3OCOc3c2)C1=O

InChI Key InChIKey=WOXKDUGGOYFFRN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532257   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532257(CHEMBL1671905)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human His-tagged PDE5A catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532257(CHEMBL1671905)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human His-tagged PDE5A catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532257(CHEMBL1671905)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532257(CHEMBL1671905)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed