BDBM50532210 CHEBI:67078::DELTA9-TETRAHYDROCANNABINOLIC ACID A

SMILES [H][C@@]12CCC(C)=C[C@@]1([H])c1c(O)c(C(O)=O)c(CCCCC)cc1OC2(C)C

InChI Key InChIKey=UCONUSSAWGCZMV-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50532210   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using [14C]-N-palmitoylethanolamine as substrate measured after 30 mins by beta-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAAH in rat brain membranes using [14C]-AEA as substrate measured after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in COS7 cells using [14C]-oleoyl-2-arachidonoyl-glycerol as substrate measured after 20 mins by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University Clinic Hospital of Valencia

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataIC50: 470nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50532210(DELTA9-TETRAHYDROCANNABINOLIC ACID A | CHEBI:67078)
Affinity DataKi:  6.50E+3nMAssay Description:Non-competitive inhibition of human LDHA assessed as reduction in lactate production using pyruvate as substrate in presence of NADH by Lineweaver-Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed