BDBM50532178 CHEMBL4460662

SMILES CCc1ccc(COc2ccc(cc2OC)C2CN(C2)C(=O)c2cc(OCCN3C[C@H](O)[C@H](O)C3)ccn2)cc1

InChI Key InChIKey=GGOSNMGBIHDZJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50532178   

LigandPNGBDBM50532178(CHEMBL4460662)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532178(CHEMBL4460662)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532178(CHEMBL4460662)
Affinity DataIC50: 41nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed