BDBM50531859 CHEMBL4475960

SMILES CCc1nc(C(N)=O)c(Nc2ccc3OCC4CN(CCN4C(=O)c3c2)C(C)C)nc1NC1CCOCC1

InChI Key InChIKey=HPZJQYDRAYLNHK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531859   

TargetTyrosine-protein kinase receptor UFO(Human)
Shanghai University

Curated by ChEMBL

LigandBDBM50531859(CHEMBL4475960)Copy SMILESCopy InChI

Affinity DataIC50: 216nMAssay Description:Inhibition of AXL (unknown origin) using poly (Glu, Tyr) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetTranscription factor ETV6/Tyrosine-protein kinase receptor UFO(Human)
Shanghai University

Curated by ChEMBL

LigandBDBM50531859(CHEMBL4475960)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Inhibition of TEL/AXL (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by SRB assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/27/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL