BDBM50531679 CHEMBL4558834

SMILES COc1cc(ccc1OCC(F)(F)F)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1

InChI Key InChIKey=TYXNXDGXXLIIGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531679   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531679(CHEMBL4558834)
Affinity DataIC50: 3.16E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531679(CHEMBL4558834)
Affinity DataIC50: 3.00E+7nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed