BDBM50531501 CHEMBL4563456

SMILES NS(=O)(=O)c1ccc(cc1)-c1nc(no1)C1CC1

InChI Key InChIKey=QRGXANRYPQYSJU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531501   

TargetCarbonic anhydrase 9(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50531501(CHEMBL4563456)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human carbonic anhydrase 9 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50531501(CHEMBL4563456)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50531501(CHEMBL4563456)
Affinity DataKi:  27nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed