BDBM50531324 CHEMBL4468518

SMILES CC(C)CCc1c(OCCOc2ccc(\C=C\C(=O)NO)cc2)ccc2CCC(=O)Oc12

InChI Key InChIKey=DYUMPFUIXGFMAH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531324   

TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using Boc Lys(Ac)-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Boc Lys(Ac)-AMC as substrate preincubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 83nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed