BDBM50531174 CHEMBL4550442

SMILES [H][C@@]12C3OC(=O)[C@@]1(CCCC2(C)C)C1=C(C=C(C(C)C)C(=O)C1=O)C3=O

InChI Key

Data  8 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50531174   

TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 400nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 390nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataKd:  448nMAssay Description:Binding affinity to human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) by surface plasmon re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 390nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 389nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 400nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataKd:  448nMAssay Description:Binding affinity to human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) by surface plasmon re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531174(CHEMBL4550442)
Affinity DataIC50: 389nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed