BDBM50531171 CHEMBL4556409

SMILES Nc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C(=O)Oc4ccc(F)cc4)[C@@H](O)[C@H]3O)c(NCc3ccc(Cl)cc3)nc12

InChI Key InChIKey=FLCTUUHJVDMVRI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531171   

TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  1.40E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 24 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  1.40E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 24 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  2.00E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 2 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  2.00E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 2 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  2.50E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 0.083 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHeat shock-related 70 kDa protein 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50531171(CHEMBL4556409)
Affinity DataKi:  2.50E+3nMAssay Description:Covalent inhibition of HSP72-NBD (unknown origin) after 0.083 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed