BDBM50531021 CHEMBL4434656

SMILES COc1ccc(CC(=O)N[C@@H](Cc2cscn2)C(=O)Nc2ccc(cc2)C(=O)NO)cc1OC

InChI Key InChIKey=MFTNXGQBTCUALX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531021   

TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531021(CHEMBL4434656)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531021(CHEMBL4434656)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed