BDBM50531019 CHEMBL4537736

SMILES Cn1c(Sc2ccc(cc2)C(=O)NO)nnc1-c1cccs1

InChI Key InChIKey=GURICKSYAGJIOY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531019   

TargetCytochrome P450 3A4(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531019(CHEMBL4537736)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531019(CHEMBL4537736)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531019(CHEMBL4537736)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50531019(CHEMBL4537736)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed