BDBM50530642 CHEMBL4531058

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)cc1

InChI Key InChIKey=VGHIIWVNJHJIHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50530642   

TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed