BDBM50530582 CHEMBL4581366

SMILES CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c1cccc2OS(F)(=O)=O

InChI Key InChIKey=YVERFLKIJOIKPE-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50530582   

LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 9nMAssay Description:Displacement of AVPI-biotin from cIAP2 BIR3 domain (unknown origin) incubated for 2 hrs by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 14nMAssay Description:Displacement of AVPI-biotin from cIAP1 BIR3 domain (unknown origin) incubated for 2 hrs by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 12nMAssay Description:Displacement of AVPI-biotin from human XIAP BIR3 domain (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS cells incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 21nMAssay Description:Displacement of AVPI-biotin from cIAP2 BIR3 domain (unknown origin) preincubated for 6 hrs followed by AVPI-biotin addition for 2 hrs by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 21nMAssay Description:Displacement of AVPI-biotin from cIAP1 BIR3 domain (unknown origin) preincubated for 6 hrs followed by AVPI-biotin addition for 2 hrs by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 43nMAssay Description:Displacement of AVPI-biotin from human XIAP BIR3 domain (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS cells preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50530582(CHEMBL4581366)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed