BDBM50530161 CHEMBL4576108

SMILES COc1cc(Cl)cc(c1)-c1nn(cc1-c1ccncc1)-c1cccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)c1

InChI Key InChIKey=NCIAIIVXYRPTDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50530161   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50530161(CHEMBL4576108)
Affinity DataIC50: 251nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P-ATP] by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50530161(CHEMBL4576108)
Affinity DataIC50: 251nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P-ATP] by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed