BDBM50530043 CHEMBL4458126

SMILES C[C@H]1\C=C\CC(=O)OCCC(Oc2ccc3OCOc3c2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H]1c1ccccc1

InChI Key InChIKey=VTETVAGUQWJMEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50530043   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50530043(CHEMBL4458126)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of full length human APE1 assessed as reduction in endonuclease activity by measuring DNA cleavage of abasic sites using 6-FAM labelled tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50530043(CHEMBL4458126)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of full length human APE1 assessed as reduction in endonuclease activity by measuring DNA cleavage of abasic sites using 6-FAM labelled tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed