BDBM50529907 CHEMBL4513700

SMILES CN(C)c1ccc(cc1)C(=O)N1CCc2sc(cc2C1)C(=O)NCC(O)CN1CCc2ccccc2C1

InChI Key InChIKey=NIBDPXQBVXGVJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529907   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50529907(CHEMBL4513700)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50529907(CHEMBL4513700)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed